References

Selected engagements and the outcomes they achieved.

Here you find a selection of our projects and case studies, from AI adoption across a company to compute-heavy analytics in research. For examples that match your situation, please get in touch.

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Selected clients

  • ZüF e.V.
  • Vectoflow GmbH
  • PHARMA PERFORMANCE

What our clients say about us

AI projects

AI policy and MS365 Copilot rollout

Rollout of MS365 Copilot as a generative AI tool across the company, development of the in-house AI policy, and AI literacy training for all staff: the basics of AI, company-specific applications, and clear roles and rules.

Process-driven use case identification

Workshop to identify process-specific AI use cases across the company. The result is a set of clearly described applications with an effort-benefit ranking and a recommendation for the next steps.

Context engineering for publications

Structuring and preparing publications so that agentic AI workflows find the relevant papers. This is what makes full-text search and literature research possible in the first place.

Research and development

R package reengineering

Reengineering of an R package so that demanding, compute-heavy algorithms scale and hold up on large data sets. Approximation methods from matrix algebra made the computation ten times faster.

RShiny apps for standardised analyses

A guided analysis app for recurring evaluations: from data import through data QC, descriptive and multivariate statistics, to report generation with optional content and literature management.

Targeted data analysis, AI-supported

We build data analyses that fit your requirements exactly, in method, format and reporting. Where it helps we work AI-supported, so you get the right interpretation of your data.

Publications

Peer-reviewed articles, book chapters, talks and workshops. Work up to 2006 was published under the name Konnert.

Show all 37 publications

2025

  1. Ott M, Bauland F, Köppl D, Ayik A, Geistanger A, Rauh M, Taibon J. An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of cortisol in human urine. Clin Chem Lab Med. 2025. doi:10.1515/cclm-2025-0522

2024

  1. Kandler K, Singh N, Bauland F, Fux E, Geistanger A, Geletneky C, Taibon J. An isotope dilution-liquid chromatography-tandem mass spectrometry based candidate reference measurement procedure for the simultaneous quantification of 25-hydroxyvitamin D3 and 25-hydroxyvitamin D2 in human serum and plasma. Clin Chem Lab Med. 2024. doi:10.1515/cclm-2024-1138
  2. Kandler K, Stadlmeier M, Singh N, Bauland F, Geistanger A, Geletneky C, Taibon J. Isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedures for the quantification of 24(R),25-dihydroxyvitamin D2 and 24(R),25-dihydroxyvitamin D3 in human serum and plasma. Clin Chem Lab Med. 2024. doi:10.1515/cclm-2024-1139
  3. Ott M, Bauland F, Fischer V, Köppl D, Gaudl A, Geistanger A, Ceglarek U, Rauh M, Taibon J. Candidate reference measurement procedure based on isotope dilution-two dimensional-liquid chromatography–tandem mass spectrometry for the quantification of androstenedione in human serum and plasma. Clin Chem Lab Med. 2024. doi:10.1515/cclm-2024-1135
  4. Ott M, Santner T, Singh N, Bauland F, Köppl D, Gaudl A, Geistanger A, Ceglarek U, Rauh M, Geletneky C, Taibon J. An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of 17β-estradiol in human serum and plasma. Clin Chem Lab Med. 2024. doi:10.1515/cclm-2024-1255
  5. Ott M, Singh N, Bauland F, Köppl D, Kandler K, Gaudl A, Geistanger A, Ceglarek U, Rauh M, Geletneky C, Taibon J. An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of cortisol in human serum and plasma. Clin Chem Lab Med. 2024. doi:10.1515/cclm-2024-0879
  6. Ott M, Singh N, Kubicova M, Bauland F, Köppl D, Gaudl A, Geistanger A, Ceglarek U, Rauh M, Geletneky C, Taibon J. An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of cortisone in human serum and plasma. Clin Chem Lab Med. 2024. doi:10.1515/cclm-2024-1478
  7. Schierscher T, Salzmann L, Singh N, Seitz M, Wild J, Schäfer C, Bauland F, Geistanger A, Risch L, Geletneky C, Seger C, Taibon J. Isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedures for the quantification of total and free phenytoin in human serum and plasma. Clin Chem Lab Med. 2024. doi:10.1515/cclm-2024-0858
  8. Schierscher T, Salzmann L, Singh N, Schäfer C, Sungauer L, Bauland F, Geistanger A, Risch L, Geletneky C, Seger C, Taibon J. An isotope dilution-liquid-chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of mycophenolic acid in human serum and plasma. Clin Chem Lab Med. 2024. doi:10.1515/cclm-2024-0860
  9. Schierscher T, Singh N, Kobel A, Wild J, Bauland F, Geistanger A, Risch L, Geletneky C, Seger C, Taibon J. An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure for the quantification of carbamazepine-10,11-epoxide in human serum and plasma. Clin Chem Lab Med. 2024;62(7):1339-51. doi:10.1515/cclm-2023-1045
  10. Schierscher T, Salzmann L, Singh N, Bachmann M, Bauland F, Geistanger A, Risch L, Geletneky C, Seger C, Taibon J. An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure for the quantification of carbamazepine in human serum and plasma. Clin Chem Lab Med. 2024;62(7):1301-13. doi:10.1515/cclm-2023-0943
  11. Schierscher T, Salzmann L, Singh N, Wild J, Fischer V, Bauland F, Geistanger A, Risch L, Geletneky C, Seger C, Taibon J. An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure for the quantification of zonisamide in human serum and plasma. Clin Chem Lab Med. 2024;62(7):1288-300. doi:10.1515/cclm-2023-0736
  12. Schierscher T, Salzmann L, Singh N, Fischer V, Kobel A, Bauland F, Geistanger A, Risch L, Geletneky C, Seger C, Taibon J. An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure (RMP) for the quantification of primidone in human serum and plasma. Clin Chem Lab Med. 2024;62(7):1327-38. doi:10.1515/cclm-2023-1032
  13. Schierscher T, Salzmann L, Singh N, Bachmann M, Kobel A, Wild J, Bauland F, Geistanger A, Risch L, Geletneky C, Seger C, Taibon J. An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure (RMP) for the quantification of phenobarbital in human serum and plasma. Clin Chem Lab Med. 2024;62(7):1314-26. doi:10.1515/cclm-2023-1104

2023

  1. Salzmann L, Spescha T, Singh N, Schierscher T, Bachmann M, Bauland F, Geistanger A, Risch L, Geletneky C, Seger C, Taibon J. An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure (RMP) for the quantification of lamotrigine in human serum and plasma. Clin Chem Lab Med. 2023;61(11):1930-41. doi:10.1515/cclm-2022-0997
  2. Salzmann L, Wild J, Singh N, Schierscher T, Liesch F, Bauland F, Geistanger A, Risch L, Geletneky C, Seger C, Taibon J. An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure (RMP) for the quantification of gabapentin in human serum and plasma. Clin Chem Lab Med. 2023;61(11):1955-66. doi:10.1515/cclm-2022-0998
  3. Salzmann L, Spescha T, Singh N, Kobel A, Fischer V, Schierscher T, Bauland F, Geistanger A, Risch L, Geletneky C, Seger C, Taibon J. An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure for the quantification of topiramate in human serum and plasma. Clin Chem Lab Med. 2023;61(11):1942-54. doi:10.1515/cclm-2022-1273
  4. Taibon J, Santner T, Singh N, Cheikh Ibrahim S, Babitzki G, Köppl D, Gaudl A, Geistanger A, Ceglarek U, Rauh M, Geletneky C. An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure (RMP) for the quantification of aldosterone in human serum and plasma. Clin Chem Lab Med. 2023;61(11):1902-16. doi:10.1515/cclm-2022-0996
  5. Kobel A, Schierscher T, Singh N, Salzmann L, Liesch F, Bauland F, Geistanger A, Risch L, Geletneky C, Seger C, Taibon J. An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure for the quantification of levetiracetam in human serum and plasma. Clin Chem Lab Med. 2023;61(11):1967-77. doi:10.1515/cclm-2022-1038
  6. Engel A, Ruhe L, Singh N, Wright JA, Liesch F, Bauland F, Ostermann AI, Sumalowitsch T, Schweinsberg VJT, Geistanger A, Hegel JK, Geletneky C, Taibon J. An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure (RMP) for the quantification of methotrexate in human serum and plasma. Clin Chem Lab Med. 2023;61(11):1917-29. doi:10.1515/cclm-2022-1001

2020-2022

  1. Geistanger A, Braese K, Laubender R. Automated data analytics workflow for stability experiments based on regression analysis. J Mass Spectrom Adv Clin Lab. 2022.
  2. Laubender R, Geistanger A. Selection of within-run quality control rules for laboratory biomarkers. Stat Med. 2021.
  3. Gradl K, Taibon J, Singh N, Albrecht E, Geistanger A, Pongratz S, Hutzler S, Mayer M, Kleinschmidt C, Geletneky C, Hofmann V, Köppl D, Rauh M, Kobold U. An isotope dilution LC–MS/MS-based candidate reference method for the quantification of androstenedione in human serum and plasma. Clin Mass Spectrom. 2020;16:1-10. doi:10.1016/j.clinms.2020.01.003

2015

  1. Anderson R, Anckaert E, Bosch E, Dewailly D, Dunlop CE, Fehr D, Nardo L, Smitz J, Tremellen K, Denk B, Geistanger A, Hund M. Prospective study into the value of the automated Elecsys antimüllerian hormone assay for the assessment of the ovarian growing follicle pool. Fertil Steril. 2015;103(4):1074-80.e4.
  2. Korse CM, Holdenrieder S, Zhi XY, Zhang X, Qiu L, Geistanger A, et al. Multicenter evaluation of a new progastrin-releasing peptide (ProGRP) immunoassay across Europe and China. Clin Chim Acta. 2015;438:388-95.

2008

  1. Geistanger A, Berding C, Vorberg E, Herlan M. Local regression: a new approach for measurement system comparison. Clin Chem Lab Med. 2008;46(9):1211-9.
  2. Geistanger A, Berding C, Arends S. Statistical methods for monitoring the relationship between the IFCC reference measurement procedure for hemoglobin A1c and the designated comparison methods in the US, Japan, and Sweden. Clin Chem. 2008;54(8):1379-85.
  3. Winzenborg I, Geistanger A, Stadtmüller U. Multivariate and functional clustering applied to measurements of laboratory analysis systems. Proc AMCTM. 2008:78.

2004-2006

  1. Konnert A, Berding C, Arends S. Uncertainty calculation of calibrators and controls of laboratory diagnostic assays. Clin Chem Lab Med. 2006;44(10):1175-82.
  2. Konnert A, Berding C, Arends S, Schubert S, et al. Uncertainty calculation for calibrators of the IFCC HbA1c standardization network. Accredit Qual Assur. 2006;11:319-28.
  3. Konnert A, Berding C, Arends S, et al. Statistical rules for laboratory networks. J Test Eval. 2006;34(2):128-34.
  4. Konnert A. Method comparison studies between different standardization networks. Proc AMCTM. 2005.
  5. Berding C, Konnert A. The statistical basis of standardization designs for diagnostic assays. Accredit Qual Assur. 2004;9:457-63.

Book chapters

  1. Hoffmeister S, Geistanger A. Optimal semi-split-plot designs with R. In: Applications in Statistical Computing. Cham: Springer International Publishing; 2019.

Talks and workshops

  1. Geistanger A. Uncertainty calculations for reference measurement procedures. Presented at: Mass Spectrometry Applications to the Clinical Lab (MSACL) Conference; 2023.
  2. Geistanger A. Method comparison and precision experiments: design, analysis and interpretation. Virtual workshop at: MSACLConnect; 2020. Available from: https://vimeo.com/439861782
  3. Geistanger A. MCR and VCA: two R packages to facilitate your method comparison and precision studies. Virtual workshop at: MSACLConnect; 2020. Available from: https://vimeo.com/422598683

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